Edin 500 mg (Capsule)

Unit Price: ৳ 12.50 (20's pack: ৳ 250.00)

Medicine Details

Category	Details
Generic	Cephradine
Company	Millat pharmaceuticals ltd
Also available as	Edin 250 mg capsule Edin 125 mg suspension Edin ds 250 mg suspension Edin 125 mg pediatric drop

Therapeutic Class

First generation Cephalosporins

Indications

Treatment of infections caused by Gram-positive and Gram-negative bacteria
Upper respiratory tract infections like sinusitis, pharyngitis, laryngo-tracheo bronchitis
Lower respiratory tract infections like bronchitis, lobar pneumonia, bronchopneumonia
Urinary tract infections like cystitis, urethritis, pyelonephritis
Skin and soft tissue infections like abscess, cellulitis, furunculosis, impetigo

Pharmacology

Semisynthetic broad spectrum bactericidal antibiotic
Active against both gram-positive and gram-negative microorganisms
Inhibits cross-linking process in the cell wall of bacteria, leading to lysis

Dosage & Administration

For oral administration in adults and children
For injectable administration in adults and children
Dosage adjustment necessary in renal impairment
Maximum daily dosage: 4 gm
Monitor patients with impaired renal or hepatic function

Interaction

Concomitant use with nephrotoxic drugs may increase risk of kidney damage
Diuretics and probenecid enhance possibility of renal toxicity

Contraindications

Hypersensitivity to cephalosporins

Side Effects

Gastro-intestinal disturbances
Hypersensitivity phenomena
Skin reactions
Blood disorders, immune system disorders, psychiatric disorders

Pregnancy & Lactation

No established safety in pregnancy
Use with caution in lactating mothers

Precautions & Warnings

Prolonged use may result in superinfection
Administer with care to patients hypersensitive to penicillins
May cause false positive urine glucose result

Use in Special Populations

Recommended doses for renal impairment and haemodialysis
Higher doses may be required for chronic or severe infections
Regular bacteriological and clinical monitoring required for chronic urinary tract infections

Overdose Effects

Symptoms include nausea, vomiting, diarrhoea, gastric upsets
Treatment mainly supportive
Gastric lavage may be necessary if large amount ingested

Storage Conditions

Suspension should be freshly prepared
Reconstituted Suspension should be used within 7-14 days
Injection solutions should be used within 2 hours at room temperature
Reconstituted solutions retain potency for 12 hours when stored at 5°C
Keep out of reach of children
To be dispensed only on prescription

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