Efrad 500 mg (Capsule)
Unit Price: ৳ 12.50 (32's pack: ৳ 400.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | Edruc limited |
| Also available as |
Indications
- Treatment of upper respiratory tract infections
- Treatment of lower respiratory tract infections
- Treatment of urinary tract infections
- Treatment of skin and soft tissue infections
- Effective against Staphylococci bacteria
- Effective against Streptococci bacteria
- Effective against Escherichia coli bacteria
- Effective against Klebsiella bacteria
- Effective against Proteus mirabilis bacteria
- Effective against Haemophilus influenza bacteria
- Effective against Shigella bacteria
- Effective against Salmonella bacteria
- Effective against Neisseria bacteria
Pharmacology
- Semisynthetic broad spectrum bactericidal antibiotic
- Active against both gram-positive and gram-negative microorganisms
- Effective against penicillinase producing staphylococci
- Inhibits cross-linking process in bacterial cell wall
Dosage & Administration
- Dosage for urinary tract infections in adults
- Dosage for respiratory tract infections in adults
- Dosage for skin and soft tissue infections in adults
- Dosage for children with otitis media
- Maximum daily dosage for children
- Dosage for injectable administration in adults
- Dosage for injectable administration in children
- Dosage for elderly patients
Interaction
- Increased risk of kidney damage with nephrotoxic drugs
- Enhanced renal toxicity with diuretics and probenecid
Contraindications
- Hypersensitivity to cephalosporins
Side Effects
- Gastrointestinal disturbances
- Hypersensitivity phenomena
- Skin reactions
- Possible blood disorders
- Possible immune system disorders
- Possible psychiatric and nervous system disorders
- Possible hepatobiliary and renal disorders
Pregnancy & Lactation
- Teratogenicity not demonstrated in animal studies
- Excretion in breast milk
- Caution in lactating mothers
Precautions & Warnings
- Risk of superinfection with prolonged use
- Cross-sensitivity between beta-lactam antibiotics
- Positive result in Coombs’ testing
- Potential for false positive urine glucose result
- Dosage adjustment in renal impairment
Use in Special Populations
- Recommended doses for patients with renal impairment
- Higher doses for chronic or severe infections
- Bacteriological and clinical monitoring for urinary tract infections
Overdose Effects
- Non-specific symptoms
- Nausea
- Vomiting
- Diarrhoea
- Gastric upsets
Therapeutic Class
- First generation Cephalosporins
Storage Conditions
- Freshly prepared suspension
- Reconstituted suspension shelf life
- Injection solutions shelf life
- Potency retention at 5°C
- Dispensing regulations