Eusef 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Category Details
Generic Cephradine
Company Globe pharmaceuticals ltd
Also available as
Eusef 500 mg capsule Eusef ds 250 mg suspension Eusef 125 mg pediatric drop Eusef 500 mg injection Eusef 1 gm injection

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of skin and soft tissue infections
  • Susceptible microorganisms: Staphylococci, Streptococci, Escherichia coli, Klebsiella spp, Proteus mirabilis, Haemophilus influenza, Shigella spp, Salmonella spp, Neisseria spp

Pharmacology

  • Broad-spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibition of cell wall cross-linking process
  • Lysis of bacteria due to external osmotic pressure

Dosage & Administration

  • Oral administration for adults and children
  • Injectable administration for adults and children
  • Dosage adjustment in renal impairment
  • Maximum daily dosage: 4 gm

Interaction

  • Increased risk of kidney damage with nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders

Pregnancy & Lactation

  • Excretion in breast milk
  • Caution in lactating mothers
  • Potential for dizziness

Precautions & Warnings

  • Development of superinfection with prolonged use
  • Cross-sensitivity risk in patients hypersensitive to penicillins
  • Positive result in Coombs’ testing
  • False positive urine glucose result with certain tests
  • Lactose content consideration for patients with specific intolerance

Use in Special Populations

  • Recommended doses for renal impairment
  • Higher doses for chronic or severe infections
  • Continued treatment for at least 2 to 3 days after symptoms resolve or bacteria are eradicated

Overdose Effects

  • Non-specific symptoms such as nausea, vomiting, and diarrhoea
  • Supportive treatment
  • Gastric lavage if large amount ingested

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Reconstituted suspension should be used within 7-14 days
  • Injection solutions should be used within 2 hours or 12 hours when stored at 5°C
  • Dispensing only on prescription

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