Eusef 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 50.00

Medicine Details

Category Details
Generic Cephradine
Company Globe pharmaceuticals ltd
Also available as
Eusef 500 mg capsule Eusef 125 mg suspension Eusef ds 250 mg suspension Eusef 125 mg pediatric drop Eusef 1 gm injection

Title

  • Eusef

Categories

  • Medicine
  • Pharmaceutical

Description

  • Broad spectrum bactericidal antibiotic for the treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria

Color options

  • N/A

Dimensions

  • N/A

Functions

  • Treats upper respiratory tract infections
  • Treats lower respiratory tract infections
  • Treats urinary tract infections
  • Treats skin and soft tissue infections

Materials

  • Cephradine

Technical specifications

  • Active against both gram-positive and gram-negative microorganisms

Design elements

  • Suspension should be freshly prepared
  • Solutions retain potency for 12 hours when stored at 5°C

Usability features

  • Oral administration
  • Injectable administration

Dosage

  • 500mg four times daily for adults with urinary tract infections
  • 250 to 500mg four times daily for adults with respiratory tract infections
  • 250 to 500mg four times daily for adults with skin and soft tissue infections
  • Total daily dose of 25 to 50mg/kg for children
  • Maximum daily dosage: 4 gm
  • Usual dose of 2-4 gm daily in four equally divided doses for adult injectable administration

Interaction

  • Concomitant use of nephrotoxic drugs may increase the risk of kidney damage
  • Diuretics and probenecid can enhance renal toxicity

Contraindications

  • Hypersensitivity to cephalosporins

Side effects

  • Limited essentially to gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Glossitis
  • Skin reactions
  • Glossitis
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Renal and urinary disorders
  • Liver enzyme disturbances

Pregnancy lactation

  • Safety in pregnancy has not been established
  • Excreted in breast milk
  • Caution in lactating mothers
  • May cause dizziness

Precautions warnings

  • Prolonged use may result in superinfection
  • Administer with care to patients hypersensitive to penicillins
  • May cause a false positive urine glucose result
  • Dosage adjustment is necessary in renal impairment
  • Contains lactose

Pediatric uses

  • Different doses recommended based on renal function
  • Higher doses may be required for chronic or severe infections
  • Continue treatment for at least 2 to 3 days after symptoms have resolved or bacteria have been eradicated

Overdose effects

  • Non-specific symptoms include nausea, vomiting, and diarrhoea

Drug classes

  • First generation Cephalosporins

Storage conditions

  • Eusef Suspension should be freshly prepared
  • Reconstituted Suspension should be used within 7 days if kept at room temperature or within 14 days if kept in a refrigerator
  • Eusef Injection solutions should be used within 2 hours when kept at room temperature

Indications

  • Indicated for the treatment of upper and lower respiratory tract infections
  • Indicated for the treatment of urinary tract infections
  • Indicated for the treatment of skin and soft tissue infections

Pharmacology

  • Active against infections caused by both gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in cell wall of bacteria leading to lysis

Interaction risks

  • Increased risk of kidney damage when used concomitantly with nephrotoxic drugs

Renal impairment dosage

  • Different recommended doses based on renal function

Bacteriological monitoring

  • Required throughout treatment of chronic urinary tract infections and for several months thereafter

Superinfection development

  • Prolonged use may result in the development of superinfection

Cross-sensitivity risk

  • Risk of cross-sensitivity between beta-lactam antibiotics in patients hypersensitive to penicillins

False glucose test result

  • May cause a false positive urine glucose result when specific testing solutions are used

Galactose intolerance warning

  • Contains lactose - Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine

Maximum daily dosage

  • Maximum daily dosage: 4 gm for adults

Hepatobiliary disorders

  • Rare: Liver enzyme disturbances, transient hepatitis, cholestatic jaundice

Solutions retain potency

  • Solutions retain potency for 12 hours when stored at 5°C

Storage instructions

  • Do not use later than the date of expiry
  • Keep all medicines out of the reach of children
  • To be dispensed only on the prescription of a registered physician

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