Extracef 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 90.00

Medicine Details

Category Details
Generic Cephradine
Company Aristopharma ltd
Also available as
Extracef 250 mg capsule Extracef 500 mg capsule Extracef ds 250 mg suspension Extracef 125 mg pediatric drop

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Gram-positive bacteria susceptibility
  • Gram-negative bacteria susceptibility

Pharmacology

  • Broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in cell wall

Dosage & Administration

  • Oral administration for adults
  • Oral administration for children
  • Injectable administration for adults
  • Injectable administration for children
  • Dosage adjustment in renal impairment

Interaction

  • Nephrotoxic drug interaction
  • Diuretics interaction
  • Probenecid interaction

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Glossitis
  • Skin reactions
  • Blood disorders
  • Fever
  • Serum sickness like reactions
  • Psychiatric disorders
  • Liver enzyme disturbances
  • Reversible interstitial nephritis

Pregnancy & Lactation

  • No established safety in pregnancy
  • Excreted in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Potential for superinfection
  • Cross-sensitivity between beta-lactam antibiotics
  • Positive result in Coombs’ testing
  • False positive urine glucose result
  • Lactose content caution

Use in Special Populations

  • Dosing recommendations for renal impairment
  • Dosing recommendations for haemodialysis
  • High doses may be required for chronic or severe infections

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Gastric lavage if necessary

Therapeutic Class

  • First generation cephalosporins

Storage Conditions

  • Fresh preparation of suspension
  • Reconstituted suspension shelf life
  • Injection solution shelf life
  • Color variation in reconstituted solution
  • Expiry date considerations
  • Keep out of reach of children

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