G-Cefradine 500 mg (Capsule)
Unit Price: ৳ 10.00 (4 x 5: ৳ 200.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | Gonoshasthaya pharma ltd |
| Also available as |
Indications
- Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
- Upper respiratory tract infections
- Lower respiratory tract infections
- Urinary tract infections
- Skin and soft tissue infections
- Susceptibility to specific microorganisms
Pharmacology
- Semisynthetic broad spectrum bactericidal antibiotic
- Active against both gram-positive and gram-negative microorganisms
- Inhibition of cell wall cross-linking process
- Bactericidal action due to lysis of bacteria from external osmotic pressure
Dosage & Administration
- Dosage for oral administration in adults
- Dosage for oral administration in children
- Maximum daily dosage
- Dosage for injectable administration in adults
- Dosage for injectable administration in children
- Dosing adjustments for elderly and patients with impaired renal or hepatic function
Interaction
- Nephrotoxic drug interaction risk
- Enhanced renal toxicity risk with diuretics and probenecid
Contraindications
- Hypersensitivity to cephalosporins
Side Effects
- Gastro-intestinal disturbances
- Hypersensitivity phenomena
- Skin reactions
- Rare side effects like glossitis, heartburn, dizziness, nausea, vomiting, diarrhoea, joint pains
- Rarely reported blood, immune system, psychiatric, nervous system, hepatobiliary, renal, and urinary disorders
Pregnancy & Lactation
- Lack of established safety in pregnancy
- Excretion in breast milk
- Caution in lactating mothers
- Caution about operating hazardous machinery
Precautions & Warnings
- Risk of superinfection with prolonged use
- Cross-sensitivity risk to penicillins
- Potential for false positive urine glucose result
- Dosage adjustment in renal impairment
- Lactose content caution for patients with rare hereditary problems
Use in Special Populations
- Recommended doses for patients with renal impairment
- Additional recommendations for patients on chronic, intermittent hemodialysis
- Higher doses required for chronic or severe infections
- Duration of treatment for specific infections
- Caution about transferring patients from intramuscular/intravenous therapy to oral treatment
Overdose Effects
- Non-specific symptoms like nausea, vomiting, diarrhoea, and gastric upsets
- Supportive treatment
- Potential need for gastric lavage in case of large ingestion
Therapeutic Class
- First generation Cephalosporins
Storage Conditions
- Freshly prepared suspension
- Reconstituted suspension expiry duration
- Injection solution usage duration
- Potency retention at different temperatures
- Dispensing only on the prescription of a registered physician