G-Amlo 10 mg (Tablet)
Unit Price: ৳ 4.60 (3 x 10: ৳ 138.00)
Strip Price: ৳ 46.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Gonoshasthaya pharma ltd |
| Also available as |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
- Reflex increase in coronary heart rate
Dosage & Administration
- Usual dose is 5 mg once daily for hypertension
- Maximum dose is 10 mg once daily for hypertension
- 5 to 10 mg for angina
- May be taken without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers
- No interaction between G-Amlo and Digoxin
- No interaction between G-Amlo and Cimetidine
- G-Amlo did not significantly alter the effect of Warfarin on prothrombin time
- Food does not alter the rate or extent of absorption of G-Amlo
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnancy
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Amlodipine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus
- It is recommended that nursing be discontinued while Amlodipine is administered
Precautions & Warnings
- Precaution should be taken in patients with hepatic impairment and during pregnancy and breastfeeding
Use in Special Populations
- Specific dosage for children with hypertension from 6 years to 17 years of age
- Effect of amlodipine on blood pressure in patients less than 6 years of age is not known
- Elderly patients can use G-Amlo at similar doses as younger patients
- Normal dosage regimens are recommended in the elderly
- Dosage recommendations in patients with mild to moderate hepatic impairment
- Normal dosage recommended in renal impairment
- Dosage initiation at the lowest dose in severe hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Marked and prolonged systemic hypotension
- Active cardiovascular support required
- Vasoconstrictor and intravenous calcium gluconate may be beneficial
- Gastric lavage may be worthwhile in some cases
- Charcoal use can reduce absorption rate of amlodipine
- Dialysis is not likely to be of benefit
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Store in a cool & dry place
- Protected from light