Intracef 250 mg (Capsule)
Unit Price: ৳ 6.50 (8 x 6: ৳ 312.00)
Strip Price: ৳ 39.00
Medicine Details
Category | Details |
---|---|
Generic | Cephradine |
Company | Beximco pharmaceuticals ltd |
Also available as |
Indications
- Gram-positive and Gram-negative bacterial infections
- Upper respiratory tract infections
- Lower respiratory tract infections
- Urinary tract infections
- Skin and soft tissue infections
Pharmacology
- Broad spectrum bactericidal antibiotic
- Active against gram-positive and gram-negative microorganisms
- Inhibits cross-linking process in bacteria cell wall
- Cell wall lysis due to external osmotic pressure
Dosage & Administration
- Oral administration for adults and children
- Dosage adjustment in renal impairment
- Maximum daily dosage of 4gm
- Injectable administration for adults and children
- Prophylactic dose for preoperative use
Interaction
- Increased risk of kidney damage with nephrotoxic drugs
- Enhanced renal toxicity with diuretics and probenecid
Contraindications
- Hypersensitivity to cephalosporins
Side Effects
- Gastro-intestinal disturbances
- Hypersensitivity phenomena
- Skin reactions
- Blood and lymphatic system disorders
- Immune system disorders
- Psychiatric disorders
- Nervous system disorders
- Hepatobiliary disorders
- Renal and urinary disorders
- Elevation of blood urea nitrogen and serum creatinine
Pregnancy & Lactation
- Teratogenicity not demonstrated in animal studies
- Excreted in breast milk
- Caution in lactating mothers
Precautions & Warnings
- Development of superinfection with prolonged use
- Cross-sensitivity between beta-lactam antibiotics
- Positive Coombs’ testing result
- False positive urine glucose result
- Lactose content
- Dosage adjustment in renal impairment
- Galactose intolerance precautions
Use in Special Populations
- Recommended doses for patients with renal impairment
- Additional information for all patients
- Regular bacteriological and clinical monitoring for urinary tract infections
- Transfer from intravenous to oral treatment
Overdose Effects
- Non-specific symptoms
- Supportive treatment
- Necessity of gastric lavage for large ingestions
Therapeutic Class
- First generation Cephalosporins
Storage Conditions
- Freshly prepared suspension
- Usage time frame for suspension and injection solutions
- Retain potency at 5°C
- Dispense only on prescription
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