Intracef 250 mg (Capsule)

Unit Price: ৳ 6.50 (8 x 6: ৳ 312.00)
Strip Price: ৳ 39.00

Medicine Details

Category Details
Generic Cephradine
Company Beximco pharmaceuticals ltd
Also available as
Intracef 500 mg capsule Intracef 125 mg suspension Intracef ds 250 mg suspension Intracef 125 mg pediatric drop

Indications

  • Gram-positive and Gram-negative bacterial infections
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in bacteria cell wall
  • Cell wall lysis due to external osmotic pressure

Dosage & Administration

  • Oral administration for adults and children
  • Dosage adjustment in renal impairment
  • Maximum daily dosage of 4gm
  • Injectable administration for adults and children
  • Prophylactic dose for preoperative use

Interaction

  • Increased risk of kidney damage with nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of blood urea nitrogen and serum creatinine

Pregnancy & Lactation

  • Teratogenicity not demonstrated in animal studies
  • Excreted in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Development of superinfection with prolonged use
  • Cross-sensitivity between beta-lactam antibiotics
  • Positive Coombs’ testing result
  • False positive urine glucose result
  • Lactose content
  • Dosage adjustment in renal impairment
  • Galactose intolerance precautions

Use in Special Populations

  • Recommended doses for patients with renal impairment
  • Additional information for all patients
  • Regular bacteriological and clinical monitoring for urinary tract infections
  • Transfer from intravenous to oral treatment

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Necessity of gastric lavage for large ingestions

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Usage time frame for suspension and injection solutions
  • Retain potency at 5°C
  • Dispense only on prescription

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