Intracef 125 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 80.00
Medicine Details
Category | Details |
---|---|
Generic | Cephradine |
Company | Beximco pharmaceuticals ltd |
Also available as |
Indications
- Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
- Upper respiratory tract infections
- Lower respiratory tract infections
- Urinary tract infections
- Skin and soft tissue infections
Pharmacology
- Semisynthetic broad spectrum bactericidal antibiotic
- Active against gram-positive and gram-negative microorganisms
- Inhibits cross-linking process in bacterial cell wall
- Cell wall contains peptidoglycan
Dosage & Administration
- Oral administration for adults and children
- Dosage based on site and severity of infection
- Maximum daily dosage: 4 gm
- Dosage adjustment necessary in renal impairment
Interaction
- Concomitant use of nephrotoxic drugs may increase risk of kidney damage
- Diuretics and probenecid enhance possibility of renal toxicity
Contraindications
- Hypersensitivity to cephalosporins
Side Effects
- Gastro-intestinal disturbances
- Hypersensitivity phenomena
- Skin reactions
- Blood disorders
- Immune system disorders
- Psychiatric disorders
- Nervous system disorders
- Hepatobiliary disorders
- Renal and urinary disorders
- Elevation of blood urea nitrogen
- Elevation of serum creatinine
Pregnancy & Lactation
- Safety in pregnancy not established
- Excreted in breast milk
- Caution in lactating mothers
- May cause dizziness
Precautions & Warnings
- Prolonged use may result in superinfection
- Administer with care to patients hypersensitive to penicillins
- May cause a false positive urine glucose result
- Contains lactose
Use in Special Populations
- Doses recommended for patients not on haemodialysis
- Doses recommended for patients on chronic, intermittent haemodialysis
- Higher doses may be required for chronic or severe infections
- Regular bacteriological and clinical monitoring required
Overdose Effects
- Non-specific symptoms
- Nausea
- Vomiting
- Diarrhoea
- Gastric upsets
- Gastric lavage necessary for large amount ingestion
Therapeutic Class
- First generation Cephalosporins
Storage Conditions
- Freshly prepared suspension
- Reconstituted Suspension should be used within 7-14 days
- Solutions should be used within 2 hours at room temperature
- Solutions retain potency for 12 hours when stored at 5°C
- Keep out of reach of children
- Dispensed only on prescription
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