Keprad 250 mg (Capsule)

Unit Price: ৳ 8.20 (40's pack: ৳ 328.00)

Medicine Details

Category Details
Generic Cephradine
Company Sonear laboratories ltd
Also available as
Keprad 500 mg capsule

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Susceptible microorganisms

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in bacteria cell walls
  • Cell lysis due to external osmotic pressure

Dosage & Administration

  • Oral administration for adults and children
  • Dosage for urinary tract infections, respiratory tract infections, and skin and soft tissue infections
  • Special dosage for elderly and patients with impaired renal or hepatic function
  • Injectable administration dosage for adults and children

Interaction

  • Concomitant use of nephrotoxic drugs
  • Enhanced risk of kidney damage with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Rare adverse effects on blood, immune system, psychiatric, nervous system, hepatobiliary, renal and urinary systems
  • Elevation of certain blood and serum parameters

Pregnancy & Lactation

  • No demonstrated teratogenicity in animal studies
  • Excretion in breast milk
  • Caution in lactating mothers
  • Precaution against operating hazardous machinery

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Care with patients hypersensitive to penicillins
  • Potential for positive result in Coombs' testing
  • Possibility of false positive urine glucose result
  • Dosage adjustment in renal impairment
  • Lactose content caution for specific patient groups

Use in Special Populations

  • Recommended doses for patients with renal impairment and on haemodialysis
  • Additional information for all patients
  • Caution in paediatric dosages
  • Transition from intramuscular/intravenous to oral treatment

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Possible need for gastric lavage

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Expiry and storage conditions for suspension and injection solutions
  • Dispensing only on prescription

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