Lebac 500 mg (Capsule)

Unit Price: ৳ 15.05 (5 x 6: ৳ 451.50)
Strip Price: ৳ 90.30

Medicine Details

Category Details
Generic Cephradine
Company Square pharmaceuticals plc
Also available as
Lebac 250 mg capsule Lebac 125 mg suspension Lebac forte 250 mg suspension Lebac 125 mg pediatric drop Lebac 500 mg injection

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process of bacterial cell wall
  • Cell wall lysis due to external osmotic pressure

Dosage & Administration

  • For oral and injectable administration
  • Different doses for adults, children, and elderly
  • Dosage adjustment necessary in renal impairment
  • Maximum daily dosage: 4 gm

Interaction

  • Concomitant use of nephrotoxic drugs may increase risk of kidney damage
  • Diuretics and probenecid enhance possibility of renal toxicity

Contraindications

  • Not to be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Glossitis
  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain
  • Rare blood disorders
  • Fever
  • Confusion
  • Dizziness
  • Liver enzyme disturbances
  • Reversible interstitial nephritis

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk
  • Caution in lactating mothers
  • May cause dizziness

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Administered with care to patients hypersensitive to penicillins
  • May cause false positive urine glucose result
  • Dosage adjustment necessary in renal impairment
  • Contains lactose, caution in patients with rare hereditary problems

Use in Special Populations

  • Recommended doses for patients with renal impairment, on haemodialysis
  • Higher doses may be required for chronic or severe infections
  • Regular bacteriological and clinical monitoring required for urinary tract infections

Overdose Effects

  • Non-specific symptoms like nausea, vomiting, diarrhoea and gastric upsets
  • Supportive treatment, gastric lavage if necessary

Therapeutic Class

First generation Cephalosporins

Storage Conditions

  • Freshly prepare Lebac Suspension
  • Reconstituted suspension should be used within 7-14 days
  • Injection solutions should be used within 2-12 hours
  • Reconstituted solutions may vary in color
  • Do not use later than the date of expiry
  • Keep out of reach of children
  • To be dispensed only on prescription

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