Lebac 500 mg (Capsule)

Unit Price: ৳ 15.05 (5 x 6: ৳ 451.50)

Strip Price: ৳ 90.30

Medicine Details

Category	Details
Generic	Cephradine
Company	Square pharmaceuticals plc
Also available as	Lebac 250 mg capsule Lebac 125 mg suspension Lebac forte 250 mg suspension Lebac 125 mg pediatric drop Lebac 500 mg injection

Indications

Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
Upper respiratory tract infections
Lower respiratory tract infections
Urinary tract infections
Skin and soft tissue infections

Pharmacology

Semisynthetic broad spectrum bactericidal antibiotic
Active against gram-positive and gram-negative microorganisms
Inhibits cross-linking process of bacterial cell wall
Cell wall lysis due to external osmotic pressure

Dosage & Administration

For oral and injectable administration
Different doses for adults, children, and elderly
Dosage adjustment necessary in renal impairment
Maximum daily dosage: 4 gm

Interaction

Concomitant use of nephrotoxic drugs may increase risk of kidney damage
Diuretics and probenecid enhance possibility of renal toxicity

Contraindications

Not to be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

Gastro-intestinal disturbances
Hypersensitivity phenomena
Skin reactions
Glossitis
Nausea
Vomiting
Diarrhoea
Abdominal pain
Rare blood disorders
Fever
Confusion
Dizziness
Liver enzyme disturbances
Reversible interstitial nephritis

Pregnancy & Lactation

Safety in pregnancy not established
Excreted in breast milk
Caution in lactating mothers
May cause dizziness

Precautions & Warnings

Prolonged use may result in superinfection
Administered with care to patients hypersensitive to penicillins
May cause false positive urine glucose result
Dosage adjustment necessary in renal impairment
Contains lactose, caution in patients with rare hereditary problems

Use in Special Populations

Recommended doses for patients with renal impairment, on haemodialysis
Higher doses may be required for chronic or severe infections
Regular bacteriological and clinical monitoring required for urinary tract infections

Overdose Effects

Non-specific symptoms like nausea, vomiting, diarrhoea and gastric upsets
Supportive treatment, gastric lavage if necessary

Therapeutic Class

First generation Cephalosporins

Storage Conditions

Freshly prepare Lebac Suspension
Reconstituted suspension should be used within 7-14 days
Injection solutions should be used within 2-12 hours
Reconstituted solutions may vary in color
Do not use later than the date of expiry
Keep out of reach of children
To be dispensed only on prescription

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