Lebac 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 95.00

Medicine Details

Category Details
Generic Cephradine
Company Square pharmaceuticals plc
Also available as
Lebac 250 mg capsule Lebac 500 mg capsule Lebac forte 250 mg suspension Lebac 125 mg pediatric drop Lebac 500 mg injection

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in bacteria cell wall

Dosage & Administration

  • Oral administration for adults and children
  • Injectable administration for adults and children
  • Dosage adjustment necessary in renal impairment
  • Maximum daily dosage: 4 gm

Interaction

  • Increased risk of kidney damage with concomitant use of nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Not to be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Liver and enzyme disturbances
  • Reversible interstitial nephritis

Pregnancy & Lactation

  • Animal studies have not demonstrated teratogenicity
  • Excreted in breast milk
  • Caution for lactating mothers

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Administered with care to patients hypersensitive to penicillins
  • May cause false positive urine glucose result
  • Dosage adjustment necessary in renal impairment
  • Contains lactose

Use in Special Populations

  • Recommended doses for patients not on haemodialysis
  • Recommendations for patients on chronic, intermittent haemodialysis
  • Regular bacteriological and clinical monitoring required for chronic urinary tract infections

Overdose Effects

  • Non-specific symptoms such as nausea, vomiting, and diarrhoea
  • Supportive treatment necessary
  • Gastric lavage required if large amount ingested

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Lebac Suspension should be freshly prepared
  • Reconstituted Suspension should be used within 7-14 days
  • Lebac Injection solutions should be used within 2 hours at room temperature
  • Retain potency for 12 hours when stored at 5°C
  • Medicines to be dispensed only on the prescription of a registered physician

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