Lebac 125 mg/1.25 ml (Pediatric Drops)

15 ml bottle: ৳ 65.19

Medicine Details

Category	Details
Generic	Cephradine
Company	Square pharmaceuticals plc
Also available as	Lebac 250 mg capsule Lebac 500 mg capsule Lebac 125 mg suspension Lebac forte 250 mg suspension Lebac 500 mg injection

Indications

Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
Upper respiratory tract infections: sinusitis, pharyngitis, tonsillitis, laryngo-tracheo bronchitis, otitis media
Lower respiratory tract infections: bronchitis, lobar pneumonia, bronchopneumonia
Urinary tract infections: cystitis, urethritis, pyelonephritis
Skin and soft tissue infections: abscess, cellulitis, furunculosis, impetigo

Pharmacology

Broad spectrum bactericidal antibiotic
Active against both gram-positive and gram-negative microorganisms
Inhibits cross-linking process in cell wall of bacteria

Dosage & Administration

For oral administration in adults: urinary tract infections, respiratory tract infections, skin and soft tissue infections
For oral administration in children: otitis media
Maximum daily dosage: 4 gm
For injectable administration in adults and children

Interaction

Concomitant use of nephrotoxic drugs may increase risk of kidney damage
Diuretics enhanced possibility of renal toxicity

Contraindications

Hypersensitivity to cephalosporins

Side Effects

Gastro-intestinal disturbances
Hypersensitivity phenomena
Skin reactions
Rare: glossitis, heartburn, dizziness, nausea, vomiting, diarrhoea, abdominal pain, vaginitis, candida overgrowth
Rare: Blood disorders, immune system disorders, psychiatric disorders, nervous system disorders, hepatobiliary disorders, renal and urinary disorders

Pregnancy & Lactation

Safety in pregnancy not established
Excreted in breast milk
Patients cautioned about operating hazardous machinery

Precautions & Warnings

Prolonged use may result in the development of superinfection
Administered with care to patients hypersensitive to penicillins
May cause false positive urine glucose result

Use in Special Populations

Recommended doses for patients with renal impairment
Additional Information for all patients

Overdose Effects

Non-specific symptoms: nausea, vomiting, diarrhoea, gastric upsets
Treatment is mainly supportive

Therapeutic Class

First generation Cephalosporins

Storage Conditions

Lebac Suspension should be freshly prepared
Reconstituted Suspension should be used within 7-14 days
Lebac Injection solutions should be used within 2 hours when kept at room temperature
Solutions retain potency for 12 hours when stored at 5°C

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