Lebac 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 65.19

Medicine Details

Category Details
Generic Cephradine
Company Square pharmaceuticals plc
Also available as
Lebac 250 mg capsule Lebac 500 mg capsule Lebac 125 mg suspension Lebac forte 250 mg suspension Lebac 125 mg pediatric drop

Dosage & Administration

  • For oral administration
  • For injectable administration
  • Urinary tract infections: 500mg four times daily or 1g twice daily
  • Respiratory tract infections: 250 to 500mg four times daily
  • Total daily dose of 25 to 50mg/kg given in two or four equally divided doses

Pharmacology

  • Active against gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process of cell wall
  • Bactericidal antibiotic

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Interaction

  • Concomitant use of nephrotoxic drugs may increase the risk of kidney damage
  • Diuretics and probenecid may enhance renal toxicity

Contraindications

  • Not for use in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Liver enzyme disturbances
  • Reversible interstitial nephritis

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk
  • Should be used with caution in lactating mothers

Precautions & Warnings

  • Prolonged use may result in the development of superinfection
  • Administered with care to patients hypersensitive to penicillins

Use in Special Populations

  • Doses for patients not on haemodialysis
  • Doses for patients on chronic, intermittent haemodialysis
  • Higher doses may be required for chronic or severe infections

Overdose Effects

  • Non-specific symptoms
  • Nausea, vomiting, diarrhoea, gastric upsets

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Reconstituted Suspension should be used within 7 days if kept at room temperature
  • Injection solutions should be used within 2 hours when kept at room temperature

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