Lindex 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 85.00

Medicine Details

Category Details
Generic Cephradine
Company Rangs pharmaceuticals ltd
Also available as
Lindex 250 mg capsule Lindex 500 mg capsule Lindex ds 250 mg suspension Lindex 125 mg pediatric drop Lindex 500 mg injection Lindex 1 gm injection

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of skin and soft tissue infections
  • Susceptibility to specific microorganisms

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibition of bacterial cell wall cross-linking process

Dosage & Administration

  • Oral administration for adults
  • Oral administration for children
  • Injectable administration for adults
  • Injectable administration for children
  • Dosage adjustment for elderly and patients with impaired renal or hepatic function

Interaction

  • Increased risk of kidney damage with nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Additional rare side effects such as glossitis, heartburn, dizziness

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excretion in breast milk
  • Caution in lactating mothers
  • Potential to cause dizziness

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Administration with care in patients hypersensitive to penicillins
  • Potential for positive Coombs’ testing
  • Potential for false positive urine glucose result

Use in Special Populations

  • Recommended doses for patients with renal impairment not on haemodialysis
  • Recommended doses for patients on chronic, intermittent haemodialysis
  • Additional dosage considerations for all patients
  • Caution in paediatric dosages

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Necessity of gastric lavage in case of large ingestion

Therapeutic Class

  • First generation cephalosporins

Storage Conditions

  • Fresh preparation of suspension
  • Reconstituted suspension shelf life
  • Injection solution shelf life
  • Variation in reconstituted solution color
  • Guidelines for medicine storage and dispensing

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