Hypoten 5 mg (Tablet)
Unit Price: ৳ 4.00 (30's pack: ৳ 120.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Cosmic pharma ltd |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
- Reflex increase in coronary heart rate
Dosage & Administration
- Usual dose is 5 mg once daily
- Maximum dose is 10 mg once daily
- 5 to 10 mg for angina
- May be taken without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers
- No interaction with Digoxin
- No interaction with Cimetidine
- No significant alteration with Warfarin
- Food does not alter absorption
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnancy
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- No adequate and well-controlled studies
- Not known if excreted in human milk
- Discontinue nursing while administered
Precautions & Warnings
- Hepatic impairment
- Pregnancy and breastfeeding
Use in Special Populations
- Dosage for children with hypertension from 6 to 17 years
- Effect on blood pressure in patients less than 6 years is unknown
- Elderly tolerance
- Normal dosage in renal impairment
- Dosage recommendations in hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Marked systemic hypotension
- Shock with fatal outcome
- Management of clinically significant hypotension
- Active cardiovascular support
- Attention to circulating fluid volume
- Use of vasoconstrictor
- Intravenous calcium gluconate
- Gastric lavage
- Use of charcoal
- Dialysis unlikely to be beneficial
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Keep out of reach of children
- Store in a cool & dry place
- Protected from light