Mega Cef 125 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 81.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | Hudson pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
- Upper respiratory tract infections (sinusitis, pharyngitis, tonsillitis, laryngo-tracheo bronchitis, otitis media)
- Lower respiratory tract infections (bronchitis, lobar pneumonia, bronchopneumonia)
- Urinary tract infections (cystitis, urethritis, pyelonephritis)
- Skin and soft tissue infections (abscess, cellulitis, furunculosis, impetigo)
Pharmacology
- Broad spectrum bactericidal antibiotic
- Active against gram-positive and gram-negative microorganisms
- Inhibits cross-linking process in cell wall of bacteria
Dosage & Administration
- Adult dosage for urinary tract infections, respiratory tract infections, and skin/soft tissue infections
- Children dosage for otitis media
- Maximum daily dosage
- Dosage for injectable administration in adults and children
Interaction
- Risk of kidney damage with concomitant use of nephrotoxic drugs
- Enhanced risk of renal toxicity with diuretics and probenecid
Contraindications
- Hypersensitivity to cephalosporins
Side Effects
- Gastrointestinal disturbances
- Hypersensitivity phenomena
- Skin reactions
- Various rare side effects
- Blood and lymphatic system disorders
- Immune system disorders
- Psychiatric disorders
- Nervous system disorders
- Hepatobiliary disorders
- Renal and urinary disorders
- Elevated investigation results
Pregnancy & Lactation
- No demonstrated teratogenicity in animal studies
- Excretion in breast milk
- Caution in lactating mothers
Precautions & Warnings
- Possible development of superinfection with prolonged use
- Careful administration to patients hypersensitive to penicillins
- Coombs’ testing result may be positive
- Potential for false positive urine glucose result
- Dosage adjustment in renal impairment
- Inappropriate for patients with galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption
Use in Special Populations
- Recommended doses for renal impairment
- Additional information for all patients
- Recommended duration of treatment
- Transfer from intramuscular/intravenous to oral treatment
Overdose Effects
- Non-specific symptoms
- Supportive treatment
- Necessity of gastric lavage for large ingestions
Therapeutic Class
- First generation Cephalosporins
Storage Conditions
- Freshly prepared suspension
- Shelf life of reconstituted suspension
- Shelf life of injection solutions
- Color variation in reconstituted solutions
- Storage temperature and potency retention
- Dispensing only on prescription