Mycef 500 mg (Capsule)

Unit Price: ৳ 12.54 (20's pack: ৳ 250.80)

Medicine Details

Category Details
Generic Cephradine
Company Ambee pharmaceuticals ltd
Also available as
Mycef 125 mg suspension Mycef 125 mg pediatric drop Mycef ds 250 mg suspension

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of skin and soft tissue infections
  • Effective against gram-positive bacteria
  • Effective against gram-negative bacteria
  • Susceptible microorganisms: staphylococci, streptococci, E. coli, klebsiella spp, proteus mirabilis, haemophilus influenza, salmonella spp, neisseria spp

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Active against penicillinase producing and non-producing staphylococci
  • Inhibits cross-linking process in cell wall of bacteria

Dosage & Administration

  • Dosage for adults with urinary tract infections
  • Dosage for adults with respiratory tract infections
  • Dosage for adults with skin and soft tissue infections
  • Dosage for children with different types of infections
  • Maximum daily dosage
  • Dosage for elderly and patients with impaired renal or hepatic function
  • Dosage for injectable administration in adults and children

Interaction

  • Risks of kidney damage when used with nephrotoxic drugs
  • Enhanced possibility of renal toxicity with diuretics and probenecid

Contraindications

  • Not to be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of blood urea nitrogen and serum creatinine
  • Elevation of liver enzymes

Pregnancy & Lactation

  • No demonstrated teratogenicity in animal studies
  • Excreted in breast milk
  • Caution advised in lactating mothers
  • May cause dizziness

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Administer with care to patients hypersensitive to penicillins
  • May cause a false positive urine glucose result
  • Dosage adjustment necessary in renal impairment
  • Contains lactose - caution in patients with hereditary problems of galactose intolerance

Use in Special Populations

  • Recommended doses for patients with renal impairment
  • Higher doses may be required for chronic or severe infections
  • Treatment duration for rheumatic fever or glomerulonephritis resulting from infections with haemolytic streptococci
  • Regular bacteriological and clinical monitoring required for chronic urinary tract infections

Overdose Effects

  • Non-specific symptoms
  • Gastric upsets
  • Supportive treatment
  • Gastric lavage for large ingestions

Therapeutic Class

  • First generation cephalosporins

Storage Conditions

  • Freshly prepare suspension
  • Reconstituted suspension expiry period
  • Injection solutions expiry period
  • Color variation in reconstituted solutions
  • Keep out of reach of children
  • Dispense only on prescription

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