Novadin 500 mg (Capsule)

Unit Price: ৳ 12.00 (5 x 4: ৳ 240.00)
Strip Price: ৳ 48.00

Medicine Details

Category Details
Generic Cephradine
Company Aexim pharmaceuticals ltd
Also available as
Novadin 125 mg suspension

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in cell wall of bacteria

Dosage & Administration

  • For oral administration in adults and children
  • For injectable administration in adults and children
  • Dosage adjustment in renal impairment
  • Maximum daily dosage: 4 gm

Interaction

  • Concomitant use of nephrotoxic drugs such as aminoglycosides may increase risk of kidney damage
  • Diuretics and probenecid may enhance possibility of renal toxicity

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of certain blood parameters

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk
  • Caution advised during lactation

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Administered with care to patients hypersensitive to penicillins
  • May cause false positive urine glucose result
  • Dosage adjustment necessary in renal impairment
  • Contains lactose, caution for patients with specific hereditary problems

Use in Special Populations

  • Recommended doses for patients with renal impairment
  • Higher doses may be required for chronic or severe infections
  • Regular monitoring for chronic urinary tract infections

Overdose Effects

  • Non-specific symptoms such as nausea, vomiting, diarrhoea and gastric upsets
  • Mainly supportive treatment
  • Gastric lavage may be necessary if large amount ingested

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Reconstituted Suspension should be used within 7-14 days
  • Injection solutions should be used within 2 hours at room temperature
  • Solutions retain potency for 12 hours at 5°C
  • Medicines to be dispensed only on prescription

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