Novadin 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Category Details
Generic Cephradine
Company Aexim pharmaceuticals ltd
Also available as
Novadin 500 mg capsule

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of skin and soft tissue infections
  • Susceptible microorganisms - Gram-positive and Gram-negative

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in bacterial cell walls
  • Cell wall lysis due to external osmotic pressure

Dosage & Administration

  • Oral administration for adults and children
  • Injectable administration for adults and children
  • Dosage adjustments for elderly, renal impairment
  • Maximum daily dosage
  • Preoperative dose for prophylaxis

Interaction

  • Concomitant use of nephrotoxic drugs
  • Enhanced possibility of renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Rare side effects such as glossitis, heartburn, dizziness, nausea, etc.
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excretion in breast milk
  • Caution in lactating mothers
  • Potential to cause dizziness

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Careful administration to patients hypersensitive to penicillins
  • Potential for false positive urine glucose result
  • Dosage adjustment in renal impairment
  • Lactose content and contraindications

Use in Special Populations

  • Recommended doses for renal impairment
  • Higher doses for chronic or severe infections
  • Continued treatment for persistent infections
  • Monitoring for chronic urinary tract infections
  • Paediatric dosages and transfer to oral treatment

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Gastric lavage for large ingestions

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Usage duration for reconstituted suspension and injection solutions
  • Storage temperatures and potency retention
  • Dispensing on prescription only

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