Orgacef 250 mg (Capsule)

Unit Price: ৳ 6.52 (7 x 4: ৳ 182.56)
Strip Price: ৳ 26.08

Medicine Details

Category Details
Generic Cephradine
Company Novatek pharmaceuticals ltd
Also available as
Orgacef 500 mg capsule Orgacef 125 mg suspension

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in the cell wall of bacteria
  • Lysis of bacteria due to external osmotic pressure

Dosage administration

  • Oral administration for adults and children
  • Injectable administration for adults and children
  • Dosage adjustment for elderly and patients with impaired renal or hepatic function
  • Maximum daily dosage
  • Dosage recommendations for patients on haemodialysis

Interaction

  • Nephrotoxic drug interaction
  • Diuretics and probenecid interaction

Contraindications

  • Hypersensitivity to cephalosporins

Side effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of blood urea nitrogen, serum creatinine, alanine aminotransferase, aspartate aminotransferase, total bilirubin, alkaline phosphatase

Pregnancy lactation

  • No demonstrated teratogenicity in animal studies
  • Excretion in breast milk
  • Caution in lactating mothers

Precautions warnings

  • Development of superinfection
  • Careful administration to patients hypersensitive to penicillins
  • Positive result in Coombs’ testing
  • False positive urine glucose result
  • Dosage adjustment in renal impairment
  • Lactose content caution for patients with rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption

Special populations

  • Recommended doses for patients not on haemodialysis based on Creatinine Clearance (CrCl) values
  • Additional Information for all patients
  • Caution for paediatric dosages not exceeding those specified for adults

Overdose effects

  • Non-specific symptoms of overdose
  • Supportive treatment
  • Gastric lavage if large amount ingested

Therapeutic class

  • First generation Cephalosporins

Storage conditions

  • Freshly prepared suspension
  • Reconstituted Suspension usage timeline
  • Injection solutions usage timeline
  • Potency retention under specific storage conditions
  • Dispensing only on the prescription of a registered physician

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