Orgacef 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.24

Medicine Details

Category Details
Generic Cephradine
Company Novatek pharmaceuticals ltd
Also available as
Orgacef 250 mg capsule Orgacef 500 mg capsule

Title

  • Orgacef Cephradine Capsules

Categories

  • Pharmaceuticals
  • Medicine
  • Antibiotics
  • Health & Personal Care

Description

  • Broad spectrum bactericidal antibiotic
  • Active against Gram-positive and Gram-negative microorganisms
  • Indicated for upper respiratory tract infections, lower respiratory tract infections, urinary tract infections, skin and soft tissue infections
  • Suitable for oral and injectable administration
  • Pharmacological action involves inhibition of cross-linking process in bacteria cell walls
  • Dosage varies for adults, children, and elderly
  • Contraindicated in patients with known or suspected cephalosporin hypersensitivity
  • Potential side effects include gastrointestinal disturbances and hypersensitivity reactions
  • Caution advised for use during pregnancy and lactation
  • Precautions necessary for patients with penicillin hypersensitivity, Coombs testing, urine glucose testing, and renal impairment
  • Dose adjustment required for patients with renal impairment
  • Recommended storage conditions for suspension and injection solutions

Color Options

  • White

Dimensions

  • Various capsule sizes

Functions

  • Treatment of sensitive Gram-positive and Gram-negative bacterial infections
  • Inhibits cross-linking process in bacteria cell walls
  • Bactericidal action against susceptible microorganisms

Materials

  • Cephradine

Technical Specifications

  • Dosage: 500mg, 1g for adults; 25-50mg/kg for children
  • Storage: Room temperature or refrigerator for suspension; 2 hours at room temperature or 12 hours at 5°C for injection solutions

Design Elements

  • Capsules

Usability Features

  • Freshly prepared suspension
  • Reconstituted suspension should be used within 7-14 days
  • Injection solutions retain potency for 2-12 hours based on storage conditions

Usability Functions

  • Oral administration
  • Injectable administration

Safety Features

  • Caution advised during pregnancy and lactation
  • Dose adjustment in renal impairment
  • Precautions for patients with penicillin hypersensitivity
  • Regular bacteriological and clinical monitoring for chronic urinary tract infections
  • Dispensing only on the prescription of a registered physician

Potential Interactions

  • Nephrotoxic drugs such as aminoglycosides
  • Diuretics (e.g. frusemide, ethacrynic acid)
  • Probenecid

Contraindications

  • Known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity reactions
  • Skin reactions
  • Blood disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of blood urea nitrogen, serum creatinine, and liver enzymes

Pregnancy & Lactation

  • Safety not established in pregnancy
  • Cautious use during lactation

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Administration with care to patients hypersensitive to penicillins
  • Potential false positive urine glucose result
  • Dosage adjustment necessary in renal impairment
  • Contains lactose

Use in Special Populations

  • Recommended doses for patients with renal impairment and on haemodialysis
  • Higher doses may be required for chronic or severe infections
  • Transfer from intramuscular/intravenous therapy to oral treatment

Overdose Effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Gastric upsets

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Reconstituted Suspension should be used within 7-14 days
  • Solutions retain potency for 2-12 hours based on storage conditions
  • Do not use after expiry date
  • Keep out of the reach of children

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