P-Cef 125 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 78.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | Pharmadesh laboratories ltd |
| Also available as |
Indications
- Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
- Upper respiratory tract infections
- Lower respiratory tract infections
- Urinary tract infections
- Skin and soft tissue infections
- Susceptible microorganisms to P-Cef
Pharmacology
- Bactericidal antibiotic
- Active against both gram-positive and gram-negative microorganisms
- Inhibition of cross-linking process in cell wall
- Cell wall lysis due to external osmotic pressure
Dosage & Administration
- Oral administration for adults
- Oral administration for children
- Maximum daily dosage
- Dosage for injectable administration
- Dosage for prophylaxis
Interaction
- Concomitant use of nephrotoxic drugs
- Enhanced renal toxicity with diuretics and probenecid
Contraindications
- Hypersensitivity to cephalosporins
Side Effects
- Gastro-intestinal disturbances
- Hypersensitivity phenomena
- Skin reactions
- Rare side effects
Pregnancy & Lactation
- Teratogenicity in animal studies
- Excretion in breast milk
- Caution in lactating mothers
Precautions & Warnings
- Development of superinfection
- Risk of cross-sensitivity between beta-lactam antibiotics
- Positive result in Coombs’ testing
- False positive urine glucose result
- Dosage adjustment in renal impairment
- Presence of lactose
Use in Special Populations
- Doses for patients not on haemodialysis
- Doses for patients on chronic, intermittent haemodialysis
- Recommendations for all patients
Overdose Effects
- Non-specific symptoms
- Supportive treatment
- Gastric lavage if large amount ingested
Therapeutic Class
- First generation Cephalosporins
Storage Conditions
- Freshly prepared suspension
- Reconstituted Suspension shelf life
- Injection solutions shelf life
- Storage temperature and potency retention
- Validity and dispensing regulations