Polycef 250 mg (Capsule)

Unit Price: ৳ 6.52 (5 x 4: ৳ 130.40)
Strip Price: ৳ 26.08

Medicine Details

Category Details
Generic Cephradine
Company Renata limited
Also available as
Polycef 500 mg capsule Polycef 125 mg suspension Polycef 125 mg pediatric drop Polycef ds 250 mg suspension Polycef 500 mg injection Polycef 1 gm injection

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Gram-positive microorganisms
  • Gram-negative microorganisms

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibition of cell wall formation

Dosage & Administration

  • For oral administration - Adults:
    • Urinary tract infections
    • Respiratory tract infections
    • Skin and soft tissue infections
  • For oral administration - Children:
    • Total daily dose
    • Otitis media
    • Maximum daily dosage
  • For injectable administration - Adult:
    • Usual dose
    • Prophylaxis
  • For injectable administration - Children:
    • Dose in severe infection

Interaction

  • Nephrotoxic drugs: Increased risk of kidney damage
  • Diuretics and probenecid: Enhanced possibility of renal toxicity

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances: Limited essentially
  • Hypersensitivity phenomena: More likely in individuals with history of allergy, asthma, hay fever or urticaria
  • Rare reactions:
    • Glossitis
    • Heartburn
    • Dizziness
    • Nausea
    • Vomiting
    • Diarrhoea
    • Abdominal pain
    • Vaginitis
    • Candida overgrowth

Pregnancy & Lactation

  • Excretion in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Superinfection: Prolonged use may result in development
  • Cross-sensitivity: Risk to patients hypersensitive to penicillins
  • Coombs’ testing: May cause a positive result
  • Urine glucose result: May cause a false positive result
  • Renal impairment: Dosage adjustment necessary
  • Lactose content: Contains lactose

Use in Special Populations

  • Renal Impairment: Recommended doses for patients not on haemodialysis
  • Additional Information:
    • Higher doses for chronic or severe infections
    • Continued treatment for at least 2 to 3 days after symptoms have resolved
    • Regular monitoring for chronic urinary tract infections

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Gastric lavage if necessary

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared Suspension
  • Reconstituted Suspension usage timeframe
  • Polycef Injection solutions usage timeframe
  • Validity period
  • Safety precautions

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