Polycef 125 mg/1.25 ml (Pediatric Drops)
15 ml bottle: ৳ 62.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | Renata limited |
| Also available as |
Indications
- Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
- Upper respiratory tract infections: sinusitis, pharyngitis, tonsillitis, laryngo-tracheo bronchitis, otitis media
- Lower respiratory tract infections: bronchitis, lobar pneumonia, bronchopneumonia
- Urinary tract infections: cystitis, urethritis, pyelonephritis
- Skin and soft tissue infections: abscess, cellulitis, furunculosis, impetigo
Pharmacology
- Broad spectrum bactericidal antibiotic
- Active against gram-positive and gram-negative microorganisms
- Active against penicillinase producing and nonproducing staphylococci
- Inhibition of cross-linking process in cell wall of bacteria
Dosage & Administration
- Oral administration for adults, children, and elderly
- Injectable administration for adults and children
- Dosage adjustment in renal impairment
Interaction
- Increased risk of kidney damage with nephrotoxic drugs
- Enhanced renal toxicity with diuretics and probenecid
Contraindications
- Known or suspected hypersensitivity to cephalosporins
Side Effects
- Gastro-intestinal disturbances
- Hypersensitivity phenomena
- Skin reactions
- Glossitis
- Dizziness
- Nausea
- Vomiting
- Diarrhoea
- Abdominal pain
Pregnancy & Lactation
- Safety not established in pregnancy
- Excretion in breast milk
- Caution in lactating mothers
Precautions & Warnings
- Development of superinfection with prolonged use
- Cross-sensitivity between beta-lactam antibiotics
- Positive result in Coombs’ testing
- False positive urine glucose result
Use in Special Populations
- Recommended doses for patients with renal impairment
- Higher doses for chronic or severe infections
Overdose Effects
- Non-specific symptoms like nausea, vomiting, diarrhea, gastric upsets
- Supportive treatment
- Gastric lavage if large amount ingested
Therapeutic Class
- First generation Cephalosporins
Storage Conditions
- Freshly prepared suspension
- Reconstituted suspension usable within 7-14 days
- Injection solutions usable within 2-12 hours based on storage temperature
- Dispensing only on the prescription of a registered physician