Polycef DS 250 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 132.00

Medicine Details

Category Details
Generic Cephradine
Company Renata limited
Also available as
Polycef 250 mg capsule Polycef 500 mg capsule Polycef 125 mg suspension Polycef 125 mg pediatric drop Polycef 500 mg injection Polycef 1 gm injection

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections: sinusitis, pharyngitis, tonsillitis, laryngo-tracheo bronchitis, otitis media
  • Lower respiratory tract infections: bronchitis (acute and chronic), lobar pneumonia, bronchopneumonia
  • Urinary tract infections: cystitis, urethritis, pyelonephritis
  • Skin and soft tissue infections: abscess, cellulitis, furunculosis, impetigo

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in bacteria's cell wall

Dosage & Administration

  • Oral administration for adults with varying doses based on infection severity
  • Oral administration for children with total daily dose based on body weight
  • Injectable administration with usual doses for adults and children

Interaction

Risk of kidney damage with concomitant use of nephrotoxic drugs

Contraindications

Not to be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity reactions
  • Skin reactions
  • Various rare side effects in different body systems

Pregnancy & Lactation

Cautious use in pregnancy and lactation due to excretion in breast milk

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Careful administration to patients hypersensitive to penicillins
  • May cause false positive urine glucose result in certain tests
  • Dosage adjustment required in renal impairment
  • Contains lactose, not suitable for certain hereditary conditions

Use in Special Populations

Specific recommended doses for patients with renal impairment

Overdose Effects

Non-specific symptoms like nausea, vomiting, diarrhoea

Therapeutic Class

First generation Cephalosporins

Storage Conditions

Freshly prepared suspension to be used within specific timeframes, injections retain potency for specific durations

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