Polycef 1 gm/vial (IM/IV Injection)

1 gm vial: ৳ 90.00

Medicine Details

Category Details
Generic Cephradine
Company Renata limited
Also available as
Polycef 250 mg capsule Polycef 500 mg capsule Polycef 125 mg suspension Polycef 125 mg pediatric drop Polycef ds 250 mg suspension Polycef 500 mg injection

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of skin and soft tissue infections
  • Susceptibility to specific microorganisms

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in bacteria cell wall
  • Formation of cell wall with pores leading to bacterial lysis

Dosage & Administration

  • Variety of dosage for different types and severity of infections
  • Different dosages for adults, children, and elderly
  • Injectable administration for prophylaxis and treatment

Interaction

  • Increased risk of kidney damage with nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Possible skin reactions
  • Rare effects on blood, immune system, psychiatric and nervous system, hepatobiliary, renal and urinary system, and investigations

Pregnancy & Lactation

  • Safety not established in pregnancy
  • Excretion in breast milk
  • Caution in lactating mothers due to potential effects on infants

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Careful administration to penicillin-hypersensitive patients
  • Potential positive Coombs’ testing
  • Possibility of false positive urine glucose result

Use in Special Populations

  • Recommended doses for patients with renal impairment and on haemodialysis
  • Higher doses for chronic or severe infections
  • Regular monitoring for chronic urinary tract infections

Overdose Effects

  • Non-specific symptoms such as nausea, vomiting, and diarrhea
  • Supportive treatment with possible gastric lavage

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Fresh preparation of Polycef Suspension
  • Limited storage duration for reconstituted Suspension and Injection solutions
  • Storage temperature and potency retention
  • Dispensing only on prescription

Related Brands