Procef 500 mg (Capsule)

Unit Price: ৳ 15.00 (5 x 4: ৳ 300.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Cephradine
Company Incepta pharmaceuticals ltd
Also available as
Procef 250 mg capsule Procef 125 mg suspension Procef fort 250 mg suspension Procef 125 mg pediatric drop Procef 500 mg injection Procef 1 gm injection

Indications

  • Treatment of Gram-positive and Gram-negative bacterial infections
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process of peptidoglycan in cell walls of bacteria

Dosage & Administration

  • Dosage for oral administration in adults and children
  • Dosage for injectable administration in adults and children
  • Maximum daily dosage
  • Dosage adjustment for patients with impaired renal or hepatic function

Interaction

  • Risk of kidney damage with concomitant use of nephrotoxic drugs
  • Enhanced risk of renal toxicity with diuretics and probenecid

Contraindications

  • Not to be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of blood urea nitrogen and serum creatinine

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk
  • Caution in lactating mothers
  • Potential to cause dizziness

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Caution with patients hypersensitive to penicillins
  • Potential for positive Coombs’ testing
  • Potential for false positive urine glucose result
  • Lactose content warning
  • Recommended doses for patients with renal impairment

Use in Special Populations

  • Recommended doses based on renal impairment for patients not on haemodialysis and on chronic, intermittent haemodialysis
  • Additional information for all patients
  • Paediatric dosages should not exceed those specified for adults
  • Transfer from intramuscular/intravenous to oral treatment

Overdose Effects

  • Non-specific symptoms of overdose
  • Supportive treatment
  • Necessity of gastric lavage for large ingestion

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Reconstituted Suspension shelf life
  • Injection solutions shelf life
  • Storage temperature impact on potency
  • Dispensing on the prescription of a registered physician

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