Procef 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Category Details
Generic Cephradine
Company Incepta pharmaceuticals ltd
Also available as
Procef 250 mg capsule Procef 500 mg capsule Procef fort 250 mg suspension Procef 125 mg pediatric drop Procef 500 mg injection Procef 1 gm injection

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of skin and soft tissue infections
  • Susceptibility to specific microorganisms

Pharmacology

  • Broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in cell wall of bacteria
  • Mechanism of action
  • Cell wall of sensitive organism contains peptidoglycan
  • Formation of cell wall with many pores leading to lysis of bacteria

Dosage & Administration

  • Recommended dosage for adults for different infections
  • Total daily dose for children for various infections
  • Maximum daily dosage
  • Dosage for elderly and patients with impaired renal or hepatic function
  • Dosage for injectable administration in adults and children

Interaction

  • Risks of concomitant use of nephrotoxic drugs
  • Enhanced risk of renal toxicity with diuretics and probenecid

Contraindications

  • Patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Rare side effects
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Investigations

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excretion in breast milk
  • Caution in lactating mothers
  • Potential for causing dizziness

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Care in administration to patients hypersensitive to penicillins
  • Potential for positive Coombs’ testing
  • Possibility of false positive urine glucose result
  • Dosage adjustment in renal impairment
  • Containment of lactose

Use in Special Populations

  • Recommended doses for patients with renal impairment
  • Additional Information for all patients
  • Extended treatment for persistent infections

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Necessity for gastric lavage

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Shelf life of reconstituted suspension
  • Shelf life of injection solutions
  • Retained potency at low temperature
  • Variation in color of reconstituted solutions
  • Dispensing requirement

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