Procef 500 mg/vial (IM/IV Injection)
500 mg vial: ৳ 50.00 (4's pack: ৳ 200.00)
Medicine Details
Category | Details |
---|---|
Generic | Cephradine |
Company | Incepta pharmaceuticals ltd |
Also available as |
Indications
- Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
- Upper respiratory tract infections
- Lower respiratory tract infections
- Urinary tract infections
- Skin and soft tissue infections
Pharmacology
- Broad-spectrum bactericidal antibiotic
- Active against both gram-positive and gram-negative microorganisms
- Inhibition of cross-linking process in cell wall of bacteria
Dosage & Administration
- Adult dosage for urinary tract infections
- Adult dosage for respiratory tract infections
- Adult dosage for skin and soft tissue infections
- Children dosage for different conditions
- Maximum daily dosage
- Elderly dosage
- Injectable administration dosage for adults
- Injectable administration dosage for children
Interaction
- Nephrotoxic drug interaction
- Diuretics interaction
- Probenecid interaction
Contraindications
- Known or suspected hypersensitivity to cephalosporins
Side Effects
- Gastro-intestinal disturbances
- Hypersensitivity phenomena
- Skin reactions
- Blood and lymphatic system disorders
- Immune system disorders
- Psychiatric disorders
- Nervous system disorders
- Hepatobiliary disorders
- Renal and urinary disorders
- Investigations disorders
Pregnancy & Lactation
- Unknown teratogenicity in animal studies
- Excretion in breast milk
- Caution in lactating mothers
- Potential of causing dizziness
Precautions & Warnings
- Prolonged use leading to superinfection
- Administration to patients hypersensitive to penicillins
- Potential positive result in Coombs’ testing
- Potential false positive urine glucose result
- Dosage adjustment in renal impairment
- Lactose content caution for patients with rare hereditary problems
Use in Special Populations
- Recommended doses for patients with renal impairment
- Additional information for all patients
- Requirement for regular bacteriological and clinical monitoring
Overdose Effects
- Non-specific symptoms
- Treatment mainly supportive
- Potential need for gastric lavage
Therapeutic Class
- First generation Cephalosporins
Storage Conditions
- Freshly prepared suspension
- Reconstituted Suspension shelf life
- Procef Injection solutions shelf life
- Color variation in reconstituted solutions
- Storage temperature requirements
- Dispensing on prescription only
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