Lodipin 5 mg (Tablet)
Unit Price: ৳ 5.00 (6 x 10: ৳ 300.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Aristopharma ltd |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Calcium-channel blocker
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
- Myocardial oxygen supply
- Cardiac output
Dosage & Administration
- Hypertension: Usual dose is 5 mg once daily
- Maximum dose is 10 mg once daily
- Angina: 5 to 10 mg, lower dose for elderly and patients with hepatic insufficiency
- May be taken without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers
- No interaction between Lodipin and Digoxin in healthy volunteers
- No interaction between, Lodipin and Cimetidine in healthy volunteers
- No significant alteration of Warfarin effect on prothrombin time by Lodipin
- Food does not alter the rate or extent of absorption of Lodipin
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnant woman
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Use during pregnancy only if potential benefit justifies potential risk to the fetus
- Recommendation to discontinue nursing while Amlodipine is administered
Precautions & Warnings
- Precaution in patients with hepatic impairment
- Precaution during pregnancy and breast feeding
Use in Special Populations
- Children with hypertension from 6 years to 17 years of age
- Children under 6 years old
- Elderly patients
- Renal impairment
- Hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Marked and prolonged systemic hypotension up to shock
- Management: active cardiovascular support, monitoring of cardiac and respiratory function, elevation of extremities, attention to circulating fluid volume and urine output, vasoconstrictor, intravenous calcium gluconate, gastric lavage, use of charcoal
- Dialysis is not likely to be of benefit
Therapeutic Class
Calcium-channel blockers
Storage Conditions
Store in a cool & dry place, protected from light