Recepra 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 75.00

Medicine Details

Category Details
Generic Cephradine
Company Reliance pharmaceuticals ltd
Also available as
Recepra 500 mg capsule

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of skin and soft tissue infections
  • Active against gram-positive bacteria
  • Active against gram-negative bacteria

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Main site of action is the cell wall of bacteria
  • Inhibits cross-linking process of bacterial cell wall

Dosage & Administration

  • Oral administration for adults and children
  • Dosage adjustment for elderly, renal impairment
  • Injectable administration for adults and children
  • Maximum daily dosage is 4 gm

Interaction

  • Concomitant use of nephrotoxic drugs may increase risk of kidney damage
  • Diuretics and probenecid enhance possibility of renal toxicity

Contraindications

  • Should not be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of blood urea nitrogen, serum creatinine, liver enzymes

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Prolonged use may result in development of superinfection
  • Caution in patients hypersensitive to penicillins
  • Cephalosporins may cause a positive result in Coombs' testing
  • May cause false positive urine glucose result with certain tests
  • Dosage adjustment necessary in renal impairment
  • Contains lactose; caution in patients with rare hereditary problems

Use in Special Populations

  • Renal Impairment dosing recommendations for different levels of creatinine clearance
  • Higher doses may be required for chronic or severe infections
  • Regular bacteriological and clinical monitoring required

Overdose Effects

  • Non-specific symptoms include nausea, vomiting, diarrhea, and gastric upsets

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepare suspension
  • Reconstituted Suspension should be used within 7-14 days
  • Injection solutions should be used within 2 hours or 12 hours when stored at 5°C
  • Keep all medicines out of the reach of children

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