Rocef 250 mg (Capsule)

Unit Price: ৳ 10.00 (8 x 6: ৳ 480.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Cephradine
Company Healthcare pharmaceuticals ltd
Also available as
Rocef 500 mg capsule Rocef 125 mg suspension Rocef forte 250 mg suspension

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Susceptible microorganisms (in vitro)

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process of bacterial cell wall
  • Cell wall lysis due to external osmotic pressure

Dosage & Administration

  • Oral administration for adults and children
  • Total daily dose for different types of infections
  • Dosage adjustment for elderly and patients with impaired renal or hepatic function
  • Injectable administration dosage for adults and children

Interaction

  • Risk of kidney damage with concomitant use of nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Not for use in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Glossitis
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain
  • Vaginitis
  • Candida overgrowth
  • Blood disorders
  • Fever
  • Anaphylaxis
  • Confusion
  • Liver enzyme disturbances
  • Transient hepatitis
  • Reversible interstitial nephritis

Pregnancy & Lactation

  • Safety not established in pregnancy
  • Excreted in breast milk
  • Caution in lactating mothers
  • Potential to cause dizziness

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Cross-sensitivity to beta-lactam antibiotics
  • Risk of false positive urine glucose result
  • Dosage adjustment in renal impairment
  • Contains lactose
  • Not for patients with galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption

Use in Special Populations

  • Recommended doses for patients with renal impairment
  • Additional information for all patients
  • Higher doses may be required for chronic or severe infections

Overdose Effects

  • Non-specific symptoms
  • Nausea
  • Vomiting
  • Diarrhoea
  • Gastric upsets
  • Supportive treatment
  • Gastric lavage if large amount ingested

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Reconstituted Suspension should be used within specified timeframes
  • Injection solutions should be used within specified timeframes
  • Variation in color of reconstituted solutions does not affect potency
  • Do not use later than the date of expiry
  • Keep out of the reach of children
  • Dispense only on the prescription of a registered physician

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