Roxicef 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.30

Medicine Details

Category Details
Generic Cephradine
Company Popular pharmaceuticals ltd
Also available as
Roxicef 500 mg capsule

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Susceptible microorganisms (Gram-positive and Gram-negative)

Pharmacology

  • Semisynthetic broad-spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in the cell wall of bacteria
  • Lysis of bacteria due to external osmotic pressure

Dosage & Administration

  • Dosage for oral administration in adults and children
  • Maximum daily dosage
  • Dosage for injectable administration in adults and children
  • Dosage for elderly and patients with impaired renal or hepatic function

Interaction

  • Concomitant use with nephrotoxic drugs
  • Enhanced risk of renal toxicity with diuretics and probenecid

Contraindications

  • Known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Limited blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of blood urea nitrogen, serum creatinine, other enzymes

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excretion in breast milk
  • Caution in lactating mothers
  • Potential to cause dizziness

Precautions & Warnings

  • Development of superinfection with prolonged use
  • Administration with care to patients hypersensitive to penicillins
  • Potential positive result in Coombs’ testing
  • Potential false positive urine glucose result
  • Dosage adjustment necessary in renal impairment
  • Lactose content concerns for certain patient populations

Use in Special Populations

  • Dosing recommendations for patients with renal impairment
  • Additional dosing information for all patients
  • Considerations for paediatric dosages and persistent infections

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Potential need for gastric lavage

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Reconstituted suspension usage timeline
  • Injection solutions usage timeline
  • Storage temperature impact on solution potency
  • Dispensing only on prescription

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