Sefacin 250 mg (Capsule)

Unit Price: ৳ 7.75 (4 x 6: ৳ 186.00)
Strip Price: ৳ 46.50

Medicine Details

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Susceptible microorganisms (Gram-positive)
  • Susceptible microorganisms (Gram-negative)

Pharmacology

  • Semisynthetic
  • Bactericidal antibiotic
  • Broad spectrum
  • Target: cell wall of bacteria
  • Inhibition of cross-linking process in cell wall
  • Susceptibility to gram-positive and gram-negative microorganisms

Dosage & Administration

  • Dosage for adults and children
  • Oral administration dosage
  • Injectable administration dosage
  • Dose adjustments in renal impairment
  • Maximum daily dosage
  • Dosage for prophylaxis

Interaction

  • Concomitant use with nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders

Pregnancy & Lactation

  • Teratogenicity in animal studies
  • Excretion in breast milk
  • Caution in lactating mothers
  • Possible dizziness

Precautions & Warnings

  • Superinfection development
  • Care in patients hypersensitive to penicillins
  • Potential positive result in Coombs' testing
  • Possible false positive urine glucose result
  • Lactose content precautions

Use in Special Populations

  • Renal impairment dosage recommendations
  • Haemodialysis dosage
  • Duration of treatment
  • Bacteriological and clinical monitoring

Overdose Effects

  • Non-specific symptoms
  • Nausea
  • Vomiting
  • Diarrhoea
  • Gastric upsets
  • Supportive treatment
  • Gastric lavage

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Shelf life of reconstituted Suspension
  • Shelf life of Injection solutions
  • Effect of storage temperature on potency
  • Variation in color of reconstituted solutions
  • Dispensing regulations

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