Sefacin 125 mg/1.25 ml (Pediatric Drops)

15 ml bottle: ৳ 50.00

Medicine Details

Title

Sefacin

Categories

  • Antibiotic
  • Medication
  • Pharmaceutical

Description

Sefacin is a first-generation cephalosporin antibiotic used to treat infections caused by sensitive Gram-positive and Gram-negative bacteria. It is available in oral and injectable forms, and is effective against various upper respiratory tract infections, lower respiratory tract infections, urinary tract infections, skin and soft tissue infections, and more.

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in the bacterial cell wall

Dosage & Administration

  • Oral administration for adults and children
  • Injectable administration for adults and children
  • Dosage adjustment in renal impairment

Interaction

  • Increased risk of kidney damage with nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity reactions
  • Skin reactions
  • Glossitis
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain
  • Hepatobiliary disorders
  • Renal and urinary disorders

Pregnancy & Lactation

  • Caution in lactating mothers due to excretion in breast milk
  • No established safety in pregnancy

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Careful administration in patients hypersensitive to penicillins
  • Potential for false positive urine glucose result
  • Lactose content caution

Use in Special Populations

  • Recommended doses for renal impairment
  • Dosing considerations for haemodialysis patients
  • Special dosing for paediatrics

Overdose Effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Gastric upsets

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Suspension preparation instructions
  • Shelf life after reconstitution
  • Storage temperature considerations

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