Sefcon DS 250 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 120.35
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | Concord pharmaceuticals ltd |
| Also available as |
Title and Categories
- Sefcon DS
- Antibiotic
- First generation Cephalosporins
Pharmacological Action
- Broad spectrum bactericidal antibiotic
- Active against both gram-positive and gram-negative microorganisms
- Inhibits cross-linking process of cell wall in bacteria
- Cell wall of sensitive organism contains peptidoglycan
- Causes lysis of bacteria due to external osmotic pressure
Indications
- Urinary tract infections
- Upper respiratory tract infections
- Lower respiratory tract infections
- Skin and soft tissue infections
Dosage and Administration
- Oral administration for adults and children
- Injectable administration for adults and children
- Dosage adjustment in renal impairment
- Maximum daily dosage 4 gm
Interactions
- Nephrotoxic drugs such as aminoglycosides
- Diuretics and probenecid enhance renal toxicity
Contraindications
- Hypersensitivity to cephalosporins
Side Effects
- Gastrointestinal disturbances
- Hypersensitivity phenomena
- Skin reactions
- Blood disorders
- Immune system disorders
- Psychiatric disorders
- Nervous system disorders
- Hepatobiliary disorders
- Renal and urinary disorders
- Elevation of blood urea nitrogen
- Elevation of serum creatinine
- Elevation of liver enzymes
Pregnancy and Lactation
- Safety in pregnancy not established
- Excreted in breast milk
- Causes dizziness
Precautions and Warnings
- Prolonged use may result in superinfection
- Care in patients hypersensitive to penicillins
- May cause a positive result in Coombs’ testing
- May cause false positive urine glucose result
- Dosage adjustment necessary in renal impairment
- Contains lactose
- Not recommended for patients with rare hereditary problems
Use in Special Populations
- Dosage recommendations for renal impairment
- Higher doses may be required for chronic or severe infections
- Regular bacteriological and clinical monitoring required for chronic urinary tract infections
Overdose Effects
- Non-specific symptoms including nausea, vomiting, diarrhea, and gastric upsets
- Supportive treatment required
- Gastric lavage may be necessary
Therapeutic Class
- First generation Cephalosporins
Storage Conditions
- Freshly prepare suspension
- Reconstituted suspension should be used within 7-14 days
- Injection solutions should be used within 2 hours at room temperature
- Solutions retain potency for 12 hours when stored at 5°C
- Reconstituted solutions may vary in color
- Keep out of reach of children
- Dispensed only on prescription of a registered physician