Nelod 5 mg (Tablet)
Unit Price: ৳ 5.02 (50's pack: ৳ 251.00)
Medicine Details
Category | Details |
---|---|
Generic | Amlodipine besilate |
Company | Kemiko pharmaceuticals ltd |
Also available as |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
- Reflex increase in coronary heart rate
Dosage & Administration
- Usual dose is 5 mg once daily
- Maximum dose is 10 mg once daily
- May be taken without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers in impaired cardiac left ventricular function
- No interaction between Nelod and Digoxin in healthy volunteers
- No interaction between Nelod and Cimetidine in healthy volunteers
- Nelod did not significantly alter the effect of Warfarin on prothrombin time
- Food does not alter the rate or extent of absorption of Nelod
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnant women
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Amlodipine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus
- Nursing should be discontinued while Amlodipine is administered
Precautions & Warnings
- Precaution in patients with hepatic impairment and during pregnancy and breastfeeding
Use in Special Populations
- Dosage for children with hypertension from 6 to 17 years
- Effect of amlodipine on blood pressure in patients less than 6 years of age is not known
- Nelod used at similar doses in elderly or younger patients is equally well tolerated
- Normal dosage regimens recommended in the elderly
- Recommended dosage in renal impairment
- Dosage recommendations in patients with mild to moderate hepatic impairment
- Nelod should be initiated at the lowest dose and titrated slowly in severe hepatic impairment
Overdose Effects
- Symptoms of large overdosage
- Management of clinically significant hypotension due to amlodipine overdosage
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Store in a cool & dry place
- Protected from light