Sefin 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.55

Medicine Details

Category Details
Generic Cephradine
Company Orion pharma ltd
Also available as
Sefin 250 mg capsule Sefin 500 mg capsule Sefin ds 250 mg suspension Sefin 125 mg pediatric drop Sefin 250 mg injection Sefin 500 mg injection Sefin 1 gm injection

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Semisynthetic broad-spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Main site of action is the cell wall of bacteria

Dosage & Administration

  • Oral administration for adults and children
  • Injectable administration for adults and children
  • Dosage adjustment in renal impairment
  • Maximum daily dosage of 4 gm

Interaction

  • Increased risk of kidney damage with concomitant use of nephrotoxic drugs
  • Enhanced possibility of renal toxicity with diuretics and probenecid

Contraindications

  • Not to be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excretion in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Prolonged use may result in the development of superinfection
  • Administered with care to patients hypersensitive to penicillins
  • May cause a false positive urine glucose result
  • Lactose content precautions

Use in Special Populations

  • Renal impairment dosages
  • Additional information for all patients
  • Paediatric dosages not to exceed those for adults

Overdose Effects

  • Non-specific symptoms
  • Mainly supportive treatment required
  • Gastric lavage necessary for large ingestions

Therapeutic Class

First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Reconstituted suspension shelf life
  • Injection solution shelf life
  • Storage temperature impact on potency
  • Dispensing only on the prescription of a registered physician

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