Sefin DS 250 mg/5 ml (Powder for Suspension)
50 ml bottle: ৳ 60.42
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | Orion pharma ltd |
| Also available as |
Product Title
- Sefin DS
Product Category
- Medicine
- Antibiotic
Description
- Sefin DS is a broad-spectrum bactericidal antibiotic indicated for the treatment of various infections caused by sensitive Gram-positive and Gram-negative bacteria.
Color Options
- N/A
Dimensions
- N/A
Materials
- Cephradine
- Peptidoglycan
Pharmacological Action
- Cephradine inhibits cross-linking process in the cell wall of bacteria, causing the formation of cell wall with pores and eventual lysis of bacteria due to external osmotic pressure.
Dosage Form
- Tablets
- Suspension
- Injection
Usability Features
- Oral Administration
- Injectable Administration
Recommended Dosage
- 500mg - 1g for adults with urinary tract infections
- 250mg - 1g for adults with respiratory tract infections
- 250mg - 1g for adults with skin and soft tissue infections
- 25-50mg/kg for children
- Maximum daily dosage: 4g for adults
Interaction
- Increased risk of kidney damage when used with nephrotoxic drugs such as aminoglycosides
- Enhanced possibility of renal toxicity with diuretics and probenecid
Contraindications
- Hypersensitivity to cephalosporins
Side Effects
- Gastrointestinal disturbances
- Hypersensitivity reactions
- Skin reactions
- Blood disorders
- Liver and renal disturbances
- Elevation of blood urea nitrogen
- Serum creatinine
- Alanine aminotransferase
- Aspartate aminotransferase
- Total bilirubin
- Alkaline phosphatase
Pregnancy & Lactation
- Safety in pregnancy not established
- Excretion in breast milk, caution in lactating mothers
Precautions & Warnings
- Prolonged use may result in superinfection
- Administer with care to patients hypersensitive to penicillins
- May cause false positive urine glucose result with certain tests
- Dosage adjustment necessary in renal impairment
- Contains lactose, caution in patients with rare hereditary problems
Use in Special Populations
- Renal Impairment dosing recommendations
- Higher doses may be required for severe infections
- Regular bacteriological and clinical monitoring for chronic urinary tract infections
Overdose Effects
- Non-specific symptoms such as nausea, vomiting, and diarrhoea
Therapeutic Class
- First generation Cephalosporins
Storage Conditions
- Suspension should be freshly prepared
- Reconstituted Suspension should be used within 7-14 days
- Injection solutions should be used within 2 hours at room temperature
- Potency of solutions retained for 12 hours when stored at 5°C
- Do not use beyond expiry date
- Keep out of reach of children
- To be dispensed only on prescription of a registered physician