Sefrad 250 mg (Capsule)

Unit Price: ৳ 10.03 (5 x 4: ৳ 200.60)
Strip Price: ৳ 40.12

Medicine Details

Category Details
Generic Cephradine
Company Synovia pharma plc
Also available as
Sefrad 500 mg capsule Sefrad 125 mg suspension Sefrad ds 250 mg suspension Sefrad 125 mg pediatric drop Sefrad 500 mg injection

Product Title

  • Sefrad

Product Categories

  • Antibiotics
  • Medicine
  • Healthcare

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process of bacterial cell wall

Dosage & Administration

  • Oral administration for adults and children
  • Injectable administration for adults and children
  • Dosage adjustment in renal impairment
  • Maximum daily dosage: 4 gm

Interaction

  • Concomitant use of nephrotoxic drugs may increase risk of kidney damage
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Limited to gastro-intestinal disturbances
  • Hypersensitivity reactions
  • Skin reactions
  • Rare blood and lymphatic system disorders
  • Rare immune system disorders
  • Rare psychiatric disorders
  • Rare nervous system disorders
  • Rare hepatobiliary disorders
  • Rare renal and urinary disorders
  • Rare elevation of blood parameters

Pregnancy & Lactation

  • No demonstrated teratogenicity in animal studies
  • Excreted in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Administration with care in patients hypersensitive to penicillins
  • Cephalosporin antibiotics may cause a positive result in Coombs’ testing
  • May cause false positive urine glucose result
  • Dosage adjustment necessary in renal impairment
  • Contains lactose
  • Dosage recommendations for renal impairment patients and haemodialysis patients

Use in Special Populations

  • Dosage recommendations for patients with renal impairment and haemodialysis patients
  • Higher doses may be required for chronic or severe infections
  • Regular bacteriological and clinical monitoring required
  • Transfer from intramuscular/intravenous to oral treatment at same dosage level
  • Paediatric dosages should not exceed those specified for adults

Overdose Effects

  • Non-specific symptoms like nausea, vomiting, diarrhoea, and gastric upsets
  • Supportive treatment
  • Gastric lavage if large amount ingested

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepare Suspension
  • Use reconstituted Suspension within 7-14 days
  • Use Injection solutions within 2 hours or 12 hours if refrigerated
  • Retain potency for 12 hours when stored at 5°C
  • Do not use after expiry date
  • Keep out of reach of children
  • To be dispensed only on prescription of a registered physician

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