Sefrate 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Category	Details
Generic	Cephradine
Company	Bristol pharmaceuticals ltd
Also available as	Sefrate 500 mg capsule Sefrate 125 mg pediatric drop

Title

Sefrate Antibiotic Medicine

Category

Medicine
Antibiotics

Indications

Upper respiratory tract infections
Lower respiratory tract infections
Urinary tract infections
Skin and soft tissue infections

Pharmacology

Broad spectrum bactericidal antibiotic
Active against gram-positive and gram-negative microorganisms
Inhibits cross-linking process in cell wall of bacteria

Dosage & Administration

Oral administration for adults and children
Injectable administration for adults and children
Maximum daily dosage: 4 gm

Interaction

Increased risk of kidney damage with nephrotoxic drugs
Enhanced renal toxicity with diuretics and probenecid

Contraindications

Hypersensitivity to cephalosporins

Side Effects

Gastro-intestinal disturbances
Hypersensitivity phenomena
Skin reactions
Blood disorders
Immune system disorders
Psychiatric disorders
Nervous system disorders
Hepatobiliary disorders
Renal and urinary disorders
Elevation of blood urea nitrogen
Serum creatinine
Alanine aminotransferase
Aspartate aminotransferase
Total bilirubin
Alkaline phosphatase

Pregnancy & Lactation

Safety in pregnancy not established
Excreted in breast milk
Caution in lactating mothers

Precautions & Warnings

Prolonged use may result in superinfection
Administered with care to patients hypersensitive to penicillins
May cause false positive urine glucose result
Dosage adjustment in renal impairment
Contains lactose

Use in Special Populations

Recommended doses for patients with renal impairment and those on haemodialysis
Higher doses may be required for chronic or severe infections

Overdose Effects

Non-specific symptoms such as nausea, vomiting, diarrhoea
Treatment is mainly supportive

Therapeutic Class

First generation Cephalosporins

Storage Conditions

Reconstituted suspension should be used within 7-14 days
Injection solutions should be used within 2 hours or 12 hours when stored at 5°C
Do not use later than the date of expiry
Keep all medicines out of the reach of children

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