Sefrate 125 mg/1.25 ml (Pediatric Drops)

15 ml bottle: ৳ 50.00

Medicine Details

Title

  • Sefrate Antibiotic Medicine

Categories

  • Medicine
  • Antibiotic
  • Pharmaceutical

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of skin and soft tissue infections

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in bacterial cell walls

DosageAndAdministration

  • Oral administration for adults and children
  • Maximum daily dosage of 4gm
  • Injectable administration for adults and children
  • Dosage adjustment in renal impairment

Interaction

  • Risk of kidney damage with concomitant use of nephrotoxic drugs
  • Enhanced risk of renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

SideEffects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood disorders
  • Fever and serum sickness like reactions
  • Liver and enzyme disturbances
  • Renal disorders

PregnancyAndLactation

  • Excretion in breast milk
  • Caution in lactating mothers
  • Safety in pregnancy not established

PrecautionsAndWarnings

  • Prolonged use may result in superinfection
  • Risk of cross-sensitivity with penicillins
  • Possible false positive urine glucose result
  • Lactose content caution
  • Dosage adjustment in renal impairment

UseInSpecialPopulations

  • Dosage recommendations for renal impairment patients and haemodialysis patients

OverdoseEffects

  • Non-specific symptoms
  • Supportive treatment
  • Gastric lavage if required

TherapeuticClass

  • First generation cephalosporins

StorageConditions

  • Freshly prepare suspension
  • Reconstituted suspension expiry within 7-14 days
  • Injection solutions expiry within 2-12 hours
  • Keep out of reach of children

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