Sefril 500 mg (Capsule)

Unit Price: ৳ 15.04 (5 x 4: ৳ 300.80)
Strip Price: ৳ 60.16

Medicine Details

Category Details
Generic Cephradine
Company Acme laboratories ltd
Also available as
Sefril 250 mg capsule Sefril 125 mg suspension Sefril ds 250 mg suspension Sefril 125 mg pediatric drop

Title

  • Sefril

Categories

  • Antibiotics
  • Medication
  • Pharmaceuticals
  • Health

Description

  • Sefril is a broad-spectrum bactericidal antibiotic used for the treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria.

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Cephradine is a semisynthetic broad spectrum bactericidal antibiotic active against both gram-positive and gram-negative microorganisms.

Dosage & Administration

  • Oral administration for adults and children
  • Dosage adjustments for elderly patients or those with impaired renal or hepatic function
  • Injectable administration for adult and pediatric patients
  • Maximum daily dosage of 4 gm

Interaction

  • Concomitant use of nephrotoxic drugs may increase the risk of kidney damage
  • Diuretics and probenecid enhance the possibility of renal toxicity

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of blood urea nitrogen, serum creatinine, alanine aminotransferase, aspartate aminotransferase, total bilirubin, alkaline phosphatase

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk
  • Caution advised for lactating mothers

Precautions & Warnings

  • Prolonged use may result in the development of superinfection
  • Administer with care to patients hypersensitive to penicillins
  • May cause a false positive urine glucose result
  • Dosage adjustment necessary in renal impairment
  • Contains lactose

Use in Special Populations

  • Renal Impairment dosing recommendations
  • Additional information for all patients
  • Paediatric dosages should not exceed those specified for adults

Overdose Effects

  • Non-specific symptoms like nausea, vomiting, and diarrhea
  • Supportive treatment recommended
  • Gastric lavage may be necessary for large ingestions

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepare suspension
  • Reconstituted suspension should be used within 7-14 days
  • Injection solutions should be used within 2 hours at room temperature
  • Potency retained for 12 hours at 5°C
  • Do not use after expiry date
  • Keep out of reach of children
  • Dispensed only on prescription of a registered physician

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