Sefro DS 250 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 120.80
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | Navana pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
- Upper respiratory tract infections
- Lower respiratory tract infections
- Urinary tract infections
- Skin and soft tissue infections
Pharmacology
- Semisynthetic broad spectrum bactericidal antibiotic
- Active against gram-positive and gram-negative microorganisms
- Inhibits cross-linking process in the cell wall of bacteria
Dosage & Administration
- Dosage for adults and children for different types of infections
- Recommended dosage for oral and injectable administration
- Dosage adjustment for renal impairment
Interaction
- Increased risk of kidney damage with concomitant use of nephrotoxic drugs
- Enhanced renal toxicity with diuretics and probenecid
Contraindications
- Not to be used in patients with known or suspected hypersensitivity to cephalosporins
Side Effects
- Gastrointestinal disturbances
- Hypersensitivity reactions
- Skin reactions
- Blood and lymphatic system disorders
- Immune system disorders
- Psychiatric disorders
- Nervous system disorders
- Hepatobiliary disorders
- Renal and urinary disorders
- Elevation of blood urea nitrogen and serum creatinine
Pregnancy & Lactation
- Safety in pregnancy not established
- Excreted in breast milk
- Caution in lactating mothers
- May cause dizziness
Precautions & Warnings
- Prolonged use may result in superinfection
- Administer with care to patients hypersensitive to penicillins
- May cause a false positive urine glucose result
- Dosage adjustment necessary in renal impairment
- Contains lactose
Use in Special Populations
- Recommended doses for patients with renal impairment
- Higher doses may be required for severe infections
- Regular bacteriological and clinical monitoring for urinary tract infections
Overdose Effects
- Non-specific symptoms
- Supportive treatment
- Gastric lavage may be necessary
Therapeutic Class
- First generation Cephalosporins
Storage Conditions
- Freshly prepare suspension
- Use within specified days once reconstituted
- Store at recommended temperatures
- Keep out of the reach of children
- Dispensed only on a physician's prescription