Sefro 125 mg/1.25 ml (Pediatric Drops)

15 ml bottle: ৳ 62.00

Medicine Details

Category Details
Generic Cephradine
Company Navana pharmaceuticals ltd
Also available as
Sefro 250 mg capsule Sefro 500 mg capsule Sefro 125 mg suspension Sefro ds 250 mg suspension

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of skin and soft tissue infections
  • Susceptible microorganisms

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in cell wall of bacteria
  • Formation of cell wall with pores leading to lysis of bacteria

Dosage & Administration

    • For oral administration - Adults:
      • Dosage for urinary tract infections
      • Dosage for respiratory tract infections
      • Dosage for skin and soft tissue infections
      • Maximum daily dosage
    • For oral administration - Children:
      • Total daily dose
      • Dose for otitis media
      • Maximum daily dosage
    • For injectable administration - Adult:
      • Usual dose
      • Prophylaxis dose
    • For injectable administration - Children:
      • Dose for severe infection
  • Dosage adjustment for elderly and patients with impaired renal or hepatic function

Interaction

  • Increased risk of kidney damage with nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Other rare effects

Pregnancy & Lactation

  • No established safety in pregnancy
  • Excretion in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Potential development of superinfection
  • Risk of cross-sensitivity in patients hypersensitive to penicillins
  • Possibility of false positive urine glucose result
  • Dosage adjustment in renal impairment
  • Lactose content precautions

Use in Special Populations

  • Recommended doses for patients with renal impairment
  • Additional information for all patients
  • Restrictions on pediatric dosages
  • Transition from intramuscular/intravenous to oral treatment

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Possible need for gastric lavage

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Preparation and use of reconstituted suspension
  • Shelf life of suspension and injection solutions
  • Storage temperature effects on potency

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