Seftec 500 mg (Capsule)

Unit Price: ৳ 12.50 (20's pack: ৳ 250.00)

Medicine Details

Category Details
Generic Cephradine
Company Apc pharma ltd
Also available as
Seftec 125 mg suspension Seftec 125 mg pediatric drop

Title

  • Seftec

Categories

  • Medicine
  • Antibiotic
  • Cephalosporins

Description

  • Seftec is a broad spectrum bactericidal antibiotic effective against infections caused by both gram-positive and gram-negative microorganisms. It is indicated for the treatment of upper and lower respiratory tract infections, urinary tract infections, skin and soft tissue infections.

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Cephradine is a semisynthetic broad spectrum bactericidal antibiotic. It inhibits the cross-linking process in the cell wall of bacteria, leading to lysis due to external osmotic pressure.

Dosage & Administration

  • For oral administration:
    • Recommended dosage for adults
    • Recommended dosage for children
    • Maximum daily dosage
    • Dosage for the elderly
    • Dosage for injectable administration
  • For injectable administration:
    • Usual dose for adults
    • Dose for prophylaxis
    • Dose for children

Interaction

  • Nephrotoxic drug interactions
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Glossitis
  • Skin reactions
  • Blood disorders
  • Fever and serum sickness like reactions
  • Psychiatric and nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excretion in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Cross-sensitivity with penicillins
  • Positive urine glucose result
  • Dosage adjustment in renal impairment
  • Lactose content

Use in Special Populations

  • Renal impairment dosages
  • Recommendations for haemodialysis patients
  • Higher doses for chronic or severe infections

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Gastric lavage

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Fresh preparation of suspension
  • Storage duration of reconstituted suspension
  • Storage duration of injection solutions
  • Color variation in reconstituted solutions

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