Seftec 125 mg/1.25 ml (Pediatric Drops)

15 ml bottle: ৳ 50.00

Medicine Details

Category Details
Generic Cephradine
Company Apc pharma ltd
Also available as
Seftec 500 mg capsule Seftec 125 mg suspension

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of skin and soft tissue infections
  • Susceptibility to specific Gram-positive bacteria
  • Susceptibility to specific Gram-negative bacteria

Pharmacology

  • Broad-spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in bacteria cell wall

Dosage & Administration

  • For oral administration - Adults:
    • Dosage for urinary tract infections
    • Dosage for respiratory tract infections
    • Dosage for skin and soft tissue infections
  • For oral administration - Children:
    • Total daily dose based on body weight
    • Specific dosage for otitis media
    • Maximum daily dosage
  • For injectable administration - Adults:
    • Usual dose
    • Prophylactic dose
  • For injectable administration - Children: Dosage based on body weight

Interaction

  • Potential risk of kidney damage with nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

Hypersensitivity to cephalosporins

Side Effects

  • Common:
    • Gastrointestinal disturbances
    • Hypersensitivity phenomena
  • Occasional:
    • Glossitis
    • Heartburn
    • Dizziness
    • Nausea
    • Vomiting
    • Diarrhoea
    • Abdominal pain
  • Rare:
    • Skin reactions
    • Joint pains
    • Oedema
    • Blood disorders
    • Immune system reactions
    • Psychiatric disorders
    • Nervous system disorders
    • Hepatobiliary disorders
    • Renal and urinary disorders
    • Elevation of blood parameters

Pregnancy & Lactation

  • No demonstrated teratogenicity in animal studies
  • Excreted in breast milk
  • Caution advised for lactating mothers

Precautions & Warnings

  • Potential for superinfection with prolonged use
  • Risk of cross-sensitivity with penicillins
  • Possible positive result in Coombs’ testing
  • Potential for false positive urine glucose result
  • Dosage adjustment in renal impairment
  • Contains lactose, caution for specific conditions

Use in Special Populations

  • Renal Impairment: Recommended doses based on creatinine clearance
  • Additional Information:
    • Higher doses may be required for chronic or severe infections
    • Duration of treatment post-symptom resolution
    • Monitoring required for chronic urinary tract infections
    • Transfer from intramuscular/intravenous to oral therapy

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Potential need for gastric lavage

Therapeutic Class

First generation Cephalosporins

Storage Conditions

  • Fresh preparation of suspension
  • Usage duration of reconstituted suspension
  • Usage duration of injection solutions
  • Potency retention under specific storage conditions
  • Dispensing only on prescription of a registered physician

Related Brands