Sephar DS 250 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | Jenphar bangladesh ltd |
| Also available as |
Indications
- Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
- Upper respiratory tract infections
- Lower respiratory tract infections
- Urinary tract infections
- Skin and soft tissue infections
- Susceptible microorganisms
- Pharmacology
- Dosage & Administration
- Oral administration for adults
- Oral administration for urinary tract infections in adults
- Oral administration for respiratory tract infections in adults
- Oral administration for skin and soft tissue infections in adults
- Oral administration for children
- Maximum daily dosage
- Injectable administration for adults
- Injectable administration for children
- Interaction
- Contraindications
- Side Effects
- Pregnancy & Lactation
- Precautions & Warnings
- Use in Special Populations
- Renal Impairment Dosage
- Chronic or severe infection dosage
- Treatment duration
- Rheumatic fever prevention
- Bacteriological and clinical monitoring
- Overdose Effects
- Therapeutic Class
- Storage Conditions
Pharmacology
- Semisynthetic broad spectrum bactericidal antibiotic
- Active against gram-positive and gram-negative microorganisms
- Inhibition of cross-linking process in cell wall of bacteria
- Cell wall contains peptidoglycan
- Lysis of bacteria due to external osmotic pressure
Dosage & Administration
- Recommended adult dosage
- Recommended children dosage
- Elderly dose
- Dosage adjustment in renal or hepatic function
- Dosage in renal impairment
- Dosage in chronic, severe infections
- Duration of treatment
- Precautions for infants exposed to cephalosporins prior to labor
- False positive urine glucose result
- Lactose content
Interaction
Risk of kidney damage with nephrotoxic drugs
Contraindications
Not for patients with known or suspected hypersensitivity to cephalosporins
Side Effects
- Gastrointestinal disturbances
- Hypersensitivity phenomena
- Possible skin reactions
- Rare side effects
Pregnancy & Lactation
- No demonstrated teratogenicity in animal studies
- Excretion in breast milk
- Caution in lactating mothers
- Caution against operating hazardous machinery
Precautions & Warnings
- Prolonged use may result in superinfection
- Care in patients hypersensitive to penicillins
- Potential positive result in Coombs’ testing
- Potential false positive urine glucose result
- Dosage adjustment necessary in renal impairment
- Lactose content precautions
Use in Special Populations
- Recommended doses for renal impairment
- Additional information for all patients
- Transfer from intramuscular/intravenous therapy to oral treatment
- Duration of therapy for persistent infections
Overdose Effects
Non-specific symptoms of overdose
Therapeutic Class
First generation cephalosporins
Storage Conditions
- Freshly prepared suspension
- Storage duration for reconstituted suspension
- Injection solution storage duration
- Solution color variation
- Dispensing on prescription