Septa 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 49.00

Medicine Details

Category Details
Generic Cephradine
Company Doctors chemical works ltd
Also available as
Septa 500 mg capsule Septa 125 mg pediatric drop

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in bacterial cell walls

Dosage & Administration

  • Oral administration for adults and children
  • Dosage adjustments for elderly and patients with impaired renal or hepatic function
  • Injectable administration for adults and children
  • Prophylactic dose for preoperative use

Interaction

  • Increased risk of kidney damage with concomitant use of nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity reactions
  • Skin reactions
  • Rare side effects including glossitis, heartburn, dizziness, nausea, vomiting, diarrhoea, etc.

Pregnancy & Lactation

  • Safety not established in pregnancy
  • Excreted in breast milk
  • Caution advised for lactating mothers

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Risk of cross-sensitivity between beta-lactam antibiotics
  • May cause false positive urine glucose result
  • Lactose content and contraindications for certain rare hereditary problems

Use in Special Populations

  • Recommended doses for patients with renal impairment
  • Additional dosing information for haemodialysis patients
  • Higher doses may be required for chronic or severe infections

Overdose Effects

  • Non-specific symptoms such as nausea, vomiting, diarrhoea, and gastric upsets
  • Supportive treatment required

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Reconstituted Suspension should be used within 7-14 days based on storage temperature
  • Injection solutions should be used within 2 hours if at room temperature
  • Retain potency for 12 hours when stored at 5°C
  • Do not use beyond expiry date
  • Keep out of reach of children
  • Dispensed only on prescription

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